PiRNAs Involved in the Memory Formation of Fear-conditioning Tests Migrating from the Brain to the Germline

Lin Li

2022

Abstract

Small piRNAs regulate and manipulate gene expressions and are important for forming memories. These piRNAs are thought to be germline-specific and can help offspring inherit memories from their parents. In this paper, we conducted odor fear-conditioning tests to identify a piRNA that increased in abundance and is involved in the memory formation of the fear-conditioning test to determine how the offspring can inherit memory. A mutant piRNA is created using a virus vector and introduced into the mice brains to see if it can migrate from the brain to the germline. If the the mutant piRNA is found in the sperm cells, then we know that the piRNAs can migrate from the brain to the sperm cells and thus inherit the memory of the odor used in the odor fear conditioning test.

Paper Citation

in Harvard Style

Li L. (2022). PiRNAs Involved in the Memory Formation of Fear-conditioning Tests Migrating from the Brain to the Germline. In Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB, ISBN 978-989-758-595-1, pages 361-365. DOI: 10.5220/0011208000003443

in Bibtex Style

@conference{icbeb22,
author={Lin Li},
title={PiRNAs Involved in the Memory Formation of Fear-conditioning Tests Migrating from the Brain to the Germline},
booktitle={Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,},
year={2022},
pages={361-365},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011208000003443},
isbn={978-989-758-595-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 4th International Conference on Biomedical Engineering and Bioinformatics - Volume 1: ICBEB,
TI - PiRNAs Involved in the Memory Formation of Fear-conditioning Tests Migrating from the Brain to the Germline
SN - 978-989-758-595-1
AU - Li L.
PY - 2022
SP - 361
EP - 365
DO - 10.5220/0011208000003443