The Function of BDNF and Treatment in Neurological Disorder

Yue Dong, Kunjie Liu, Yushi Wu

2022

Abstract

Brain-derived neurotrophic factor (BDNF) is one of the most well-researched factors that thas been shown to regulate mood and stress-coping. There is growing evidence suggesting the dysfunction of the BDNF pathway is likely to cause several types of mental disorders such as Major Depressive Disorders, Stroke, and Parkinson’s Disease. This review article provides a detailed examination of the function of BDNF and how it relates to neurological diseases, particularly depression, as well as different studies and theories explaining the mechanism behind how dysfunction of the BDNF relates to depression. The article also discussed different types of treatments, including drug treatment and CRISPR, that target these neurological disorders caused by BDNF dysfunction. Despite the uncertainty in this field, there is still enough evidence suggesting that dysregulation of BDNF can be a risk factor for many neurological disorders. Studies on this topic will likely evoke new perspectives on modern treatments.

Paper Citation

in Harvard Style

Dong Y., Liu K. and Wu Y. (2022). The Function of BDNF and Treatment in Neurological Disorder. In Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH, ISBN 978-989-758-596-8, pages 254-263. DOI: 10.5220/0011269100003438

in Bibtex Style

@conference{ichih22,
author={Yue Dong and Kunjie Liu and Yushi Wu},
title={The Function of BDNF and Treatment in Neurological Disorder},
booktitle={Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,},
year={2022},
pages={254-263},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0011269100003438},
isbn={978-989-758-596-8},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 1st International Conference on Health Big Data and Intelligent Healthcare - Volume 1: ICHIH,
TI - The Function of BDNF and Treatment in Neurological Disorder
SN - 978-989-758-596-8
AU - Dong Y.
AU - Liu K.
AU - Wu Y.
PY - 2022
SP - 254
EP - 263
DO - 10.5220/0011269100003438